Qichen-lab.info
- Title
- Qi Chen Lab - University of Nevada, Reno School of Medicine
- Meta Description
- Dr. Qi Chen is a reproductive & developmental biologist at University of Nevada, Reno School of Medicine. We study sperm small RNAs and epigenetic inheritance, paticularly sperm non-coding RNAs in acquired epigenetic memory, and transgenerational epigenetic inheritance. We are also interested in studying the molecular mechanisms of Symmetry-breaking in mammalian early embryo. Our recent works focus on sperm tsRNAs (tRNA derived small RNAs) and its role in epigenetic memory, showing that sperm tsRNAs act as a type of paternal epigetic factor that contribute to intergenerational inheritance of an acquired metabolic disorder. Research from his lab add to the growing body of inheritable factors beyond DNA sequences, leading to a resurrected lamarckism, that inheritance of acquired characteristics during environmental exposure do happens under epigenetic regulations. Website: http://qichen-lab.info/
- Meta Keywords
- qi chen lab, qi chen, nevada, qichen, sperm samll RNAs, sperm tsRNA, sperm tsRNAs, tRFs, tRNA-dervied small RNAs, serum, serum tsRNAs, transgenerational epigenetic inheritance, intergenerational inheritance, non-coding RNAs, embryo development, early embryo symmetry-breaking, bistable, monostable, small biases, AQP3, AQP4, AQP5, aquaporin-3, sperm osmoadaptation, sperm osmoregulation, Nevada, Reno, University of Nevada, school of medicine, RVD, mechanosensor, osmosensor, mechanosensing, mechxnosensitive, evolution
- Technologies in use
- jQuery, jQuery UI, Angular