SITS (Safe Implementation of Treatment in Stroke) is a non-profit, research-driven, independent, international collaboration, with its base at the Karolinska Institute in Sweden. SITS is an initiative by the medical profession to provide safe implementation of stroke treatment in routine clinical practice. SITS vision is to reduce the global burden of stroke; by improving the stroke outcome, preventing recurrent stroke and find the best treatments. This will help the authorities to monitor new treatments and set new guidelines. This will also increase the quality of life for stroke patients and save lives.